Medically reviewed by P. Thornton, DipPharm Last updated on Mar 1, Premarin Vaginal Cream contains a mixture of estrogen hormones.
Conjugated estrogens vaginal cream belongs to the class of medications known as estrogen replacement therapy. Conjugated estrogens vaginal cream is used to manage vaginal and urinary menopausal symptoms such as itching, burning, dryness in or around the vagina, difficulty or burning during urination, and painful sexual intercourse. Estrogen is a hormone that is produced by the ovaries.
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Estrogen increases the risk that you will develop endometrial cancer cancer of the lining of the uterus [womb]. The longer you use estrogen, the greater the risk that you will develop endometrial cancer. If you have not had a hysterectomy surgery to remove the uterusyou may be given another medication called a progestin to take with vaginal estrogen. This may decrease your risk of developing endometrial cancer but may increase your risk of developing certain other health problems, including breast cancer.
Vaginal estrogen is a form of estrogen that is delivered by intravaginal administration. Vaginally administered estrogens are thereby exerting their effects mainly in the nearby tissue, with more limited systemic effects compared to orally administered estrogens. Vaginally administered estrogen are usually used to treat some menopausal symptoms that are isolated to the vaginavulva and urethra.
This medication is to be used vaginally. As this product may leak and stain your underwear, you are advised to wear a sanitary napkin during the treatment. Use the product for the prescribed period of time and follow the directions for use included in the package.
Vaginal dryness probably results from changes that occur when estrogen levels drop. Low estrogen causes the vagina and surrounding connective tissue to lose elasticity and the tissue that lines the vagina becomes thinner and more fragile. How does vaginal dryness feel?
Premarin vaginal cream conjugated estrogens is an estrogen hormone, which restores function lost during menopause such as vaginal dryness. The placebo bar shows how common a side effect was for people taking a sugar pill instead of Premarin vaginal cream. If you're taking Premarin vaginal cream conjugated estrogens and have your uterus, you might have a higher risk of having endometrial cancer.
Member contributors included Ruth Farrell, MD. This document reflects emerging clinical and scientific advances as of the date issued and is subject to change. The information should not be construed as dictating an exclusive course of treatment or procedure to be followed. ABSTRACT: Cancer treatment should address female-specific survivorship issues, including the hypoestrogenic-related adverse effects of cancer therapies or of natural menopause in survivors.